Issue Brief
Mar 30, 2012
The Superbug Threat explores the emergence of antibiotic-resistant bacteria and its impact on human health, as well as the shrinking pipeline of new antibiotics. More info| Summary | Type |
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Recent Outbreak Stresses Need for New AntibioticsOn August 22, researchers at the National Institute of Health released a scientific paper detailing the use of advanced genetic technology to trace a deadly infection, untreatable by nearly every antibiotic, that spread through the NIH’s Clinical Center last year. More info |
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FDA Releases Draft Guidance on Antibacterial Drug DevelopmentNearly a year after the enactment of the Generating Antibiotic Incentives Now Act, the U.S. Food and Drug Administration has released draft guidance for industry on developing antibacterial therapies for patients with unmet medical needs. More info |
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A New Pathway for Antibiotic Innovation: Exploring Drug Development for Limited PopulationsAs multidrug-resistant infections have grown more prevalent, few new antibiotics are reaching the market. This is attributed, in part, to the economic and regulatory challenges associated with their development. Recently, stakeholders have endorsed a novel regulatory pathway to approve these lifesaving drugs for use in limited patient populations — namely those at highest risk and with few or no other options. More info |
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National Public Health WeekThis year's celebration of National Public Health Week (NPHW) focuses on the theme, "Public Health is ROI: Save Lives, Save Money." Join us in recognizing the work of Pew's Health Initiatives. More info |
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Test Your Knowledge of AntibioticsNearly nine in 10 Americans recognize that antibiotics are effective treatments for fighting bacterial infections like strep throat, but more than a third mistakenly believe the drugs are also appropriate treatments for viral infections such as the common cold. Test your antibiotics IQ and take the quiz. More info |
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Drug Development for Limited Populations: A New Proposed PathwayThe lack of new antibiotics and the rise in drug resistance have rendered some serious and life-threatening infections untreatable, and the health care community is searching for ways to bring innovative new drugs to patients whose treatment options are limited or nonexistent. More info |
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The Battle on the Home Front: The Jonathan Gadsden StorySince Operations Iraqi Freedom and Enduring Freedom began, many American servicemen and women have been infected with antibiotic-resistant bacteria. While our men and women in uniform increasingly survive severe wounds sustained in combat, their injuries leave them susceptible to life-threatening, hard-to-treat infections. Marine Lance Corporal Jonathan Gadsden’s story reflects the growing need for new antibiotics that can treat these dangerous diseases, against which most drugs are useless. More info |
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Unmet Medical Need in Infectious DiseasesIntroduced more than 75 years ago, antibiotics have profoundly transformed health care. Thanks to these drugs and to advances in vaccines and infection control, many formerly devastating bacterial illnesses can be cured or contained. More info |
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Reviving the Pipeline of Life-Saving AntibioticsAntibiotic-resistant infections are a growing public health threat. At the same time, antibiotic innovation is waning. Pew, the IIDSA and PhRMA hosted a one-day conference, Reviving the Pipeline of Life-Saving Antibiotics: Exploring Solutions to Spur Innovation on September 22, 2011, exploring ways to overcome the challenges that hinder the development of new antibiotics. More info |
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MRSA: A Deadly Pathogen with Fewer and Fewer Treatment OptionsStaphylococcus aureus, or staph, is a common bacterium that exists in our environment and our bodies. Most of the time it does no harm. Sometimes, however, it can cause infection and require treatment. MRSA refers to strains of S. aureus that are resistant to the antibiotic methicillin and a host of other drugs used to treat infection. More info |
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Antibiotic Innovation: The Threat and the PipelineThe Superbug Threat explores the emergence of antibiotic resistant bacteria and its impact on human health, as well as the shrinking pipeline of new antibiotics. More info |
Issue Brief |
Testimony before the House Committee on Energy and Commerce, Subcommittee on HealthAllan Coukell, Director of Medical Programs, and Sharon Ladin, Director of the Antibiotics and Innovation Project, testify before the House Committee on Energy and Commerce, Subcommittee on Health on stimulating the development of new antibiotics urgently needed to fight serious and life-threatening bacterial infections. More info |
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MRSA on the Appalachian Trail: The Story of Steve WeiselHiking the Appalachian Trail, Steve Weisel thought little of the blisters on his feet until he discovered they were infected with life-threatening methicillin-resistant Staphylococcus aureus (MRSA) -- an increasingly common "superbug" that does not respond to first-line antibiotics. Mr. Weisel's story demonstrates the urgent need for new and innovative therapies to treat this growing threat. More info |
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The Threat of Multidrug-Resistant Infections to ChildrenExpert testimony, research, and commentary More info |
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When Multiple Bugs Strike: The Story of Alice BrennanA healthy immune system may be all the protection someone needs to overcome a bacterial infection, but once one disease takes hold, it may beget more illnesses. Such is often the case with Clostridium difficile, a potentially deadly bacterium that can flourish in the wake of other infections. Senior citizens, such as Alice Brennan, are particularly vulnerable and serve as a reminder that new and powerful antibiotics are needed as protection from dangerous bacterial threats. More info |
Issue Brief |
The lack of new antibiotics and the rise in drug resistance have rendered some serious and life-threatening infections untreatable, and the health care community is searching for ways to bring innovative new drugs to patients whose treatment options are limited or nonexistent.
Antibiotics save untold numbers of human lives every day. Modern medicine depends on their ability to treat and prevent infections such as pneumonia and staph. Yet drug-resistant bacteria are spreading and too often antibiotics are taken for granted. Test your knowledge.
Allan Coukell
Senior Director, Drugs and Medical Devices
The Pew Charitable Trusts
Nicole Mahoney
Senior Officer, Antibiotics and Innovation
The Pew Charitable Trusts
Copyright(c) 1996-2012 The Pew Charitable Trusts. All Rights Reserved.
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