"As a nation, we need to exercise greater care with our use of antibiotics, in both humans and animals, so that these medications remain effective in treating serious bacterial infections.
Twenty-six years ago, as a pediatric intern, I marveled at the power of a new class of antibiotics, the cephalosporins, in treating children with life-threatening infections.
I recall the warning of my attending physician, who foresaw the day when bacteria would develop resistance to these new drugs. At the time, I had hoped she was wrong. She wasn’t. During my residency, my training in infectious diseases, and my long practice in this community, I have watched the steady increase in resistance to this class, and to most classes, of antibiotics.
I have had to treat a child with mastoiditis, a complication of an ear infection, with four weeks of intravenous antibiotics because oral antibiotics were inadequate for the highly resistant bacteria causing the illness.
Many strains of Staphylococcus aureus, a common skin bacterium, are now resistant to multiple drugs. When treating a serious infection, such as a bone infection or pneumonia, due to this bacterium we now must start with antibiotics previously reserved for hospital-acquired infections.
While treating the infections has become more difficult, most illness-causing bacteria are still sensitive to some antibiotics. However, with continued widespread antibiotic use in humans, and overuse in animals, there will inevitably be further development of resistance. I dread the day when my colleagues and I have no effective antibiotics to treat a seriously ill child."
Nearly a year after the enactment of the Generating Antibiotic Incentives Now Act, the U.S. Food and Drug Administration has released draft guidance for industry on developing antibacterial therapies for patients with unmet medical needs.
More infoSenator Dianne Feinstein (D-CA) today introduced the Preventing Antibiotic Resistance Act, a bipartisan bill that would eliminate certain antibiotic-related practices that contribute to the rise of drug-resistant bacteria and endanger human health. The legislation is co-sponsored by Senators Susan Collins (R-ME), Kirsten Gillibrand (D-NY), Jack Reed (D-RI), Barbara Boxer (D-CA) and Maria Cantwell (D-WA).
More infoThis bibliography lists the latest published scientific and economic literature concerning the contribution of routine antibiotic use in food animals to the growing public health crisis of human antibiotic resistance. Research on how antibiotic use in food animal production contributes to the growing health crisis of antibiotic resistance dates back more than 30 years.
More infoAs multidrug-resistant infections have grown more prevalent, few new antibiotics are reaching the market. This is attributed, in part, to the economic and regulatory challenges associated with their development. Recently, stakeholders have endorsed a novel regulatory pathway to approve these lifesaving drugs for use in limited patient populations — namely those at highest risk and with few or no other options.
More infoPew Charitable Trusts today applauded Senators Kirsten Gillibrand (D-NY), Dianne Feinstein (D-CA), and Susan Collins (R-ME), for introducing the Antimicrobial Data Collection Act, which would require the U.S. Food and Drug Administration, or FDA, to report more information on the annual sales of antibiotics used among industrial farm animals. The bipartisan bill would also give the agency a deadline to finalize policies proposed last year to eliminate the use of antibiotics for growth promotion purposes in meat production.
More infoSuperChefs Against Superbugs, an initiative of the Pew Campaign on Human Health and Industrial Farming, is a movement of chefs nationwide who have expressed their support of ending the misuse and overuse of antibiotics in food animal production. As a result, the SuperChefs are urging the Food and Drug Administration to strengthen its antibiotic policies.
More infoSuperChefs Against Superbugs, an initiative of the Pew Campaign on Human Health and Industrial Farming, is a movement of chefs who want to stop the overuse of antibiotics in food animal production. On April 23, the following seven chefs visited Capitol Hill to explain why they serve meat and poultry raised without antibiotics.
More infoIt used to be easy to treat healthy children with common bacterial infections; a regimen of antibiotic pills could usually wipe out the disease. Today, patients might need to go home on intravenous antibiotics because oral therapies will no longer work. Antibiotic resistance is to blame.
More infoA past bout of salmonella led Maine resident Danielle Wadsworth to travel to Washington, D.C. this week to argue for stronger regulations to curtail the use of antibiotics in livestock farming. She took part Wednesday in "Supermoms Against Superbugs," an initiative of the Pew Campaign on Human Health and Industrial Farming.
More infoDr. Cecilia Di Pentima is in Washington, D.C., for “Supermoms against Superbugs” to push for laws to curtail the use of antibiotics in livestock farming — one of many fronts in the battle to preserve the effectiveness of the medicines. Family physicians in the South, including Tennessee, have also been identified as inadvertent purveyors of drug-resistant bacteria by prescribing too many antibiotics.
More infoEach year, tens of thousands of Americans die and hundreds of thousands are hospitalized because of bacterial infections resistant to antibiotics. Antibiotic overuse on industrial farms is a big part of the problem. The largest U.S. meat and poultry producers feed antibiotics to healthy animals over much of their lives to make them grow faster and to compensate for the overcrowded and unsanitary conditions in which they are bred and slaughtered.
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