On August 22, researchers at the National Institutes of Health released a scientific paper detailing the use of advanced genetic technology to trace a deadly infection, untreatable by nearly every antibiotic, that spread through the NIH’s Clinical Center last year. The superbug eventually infected 17 patients. Eleven died, six from bloodstream superbug infections. Nicole Mahoney, Senior Officer of the Antibiotics and Innovation Project at the Pew Health Group, says this case illustrates the need for the development of new antibiotics to treat life-threatening illnesses.
Nearly a year after the enactment of the Generating Antibiotic Incentives Now Act, the U.S. Food and Drug Administration has released draft guidance for industry on developing antibacterial therapies for patients with unmet medical needs.
Senator Dianne Feinstein (D-CA) today introduced the Preventing Antibiotic Resistance Act, a bipartisan bill that would eliminate certain antibiotic-related practices that contribute to the rise of drug-resistant bacteria and endanger human health. The legislation is co-sponsored by Senators Susan Collins (R-ME), Kirsten Gillibrand (D-NY), Jack Reed (D-RI), Barbara Boxer (D-CA) and Maria Cantwell (D-WA).
The lack of new antibiotics and the rise in drug resistance have rendered some serious and life-threatening infections untreatable, and the health care community is searching for ways to bring innovative new drugs to patients whose treatment options are limited or nonexistent. More info
This bibliography lists the latest published scientific and economic literature concerning the contribution of routine antibiotic use in food animals to the growing public health crisis of human antibiotic resistance. Research on how antibiotic use in food animal production contributes to the growing health crisis of antibiotic resistance dates back more than 30 years.
As multidrug-resistant infections have grown more prevalent, few new antibiotics are reaching the market. This is attributed, in part, to the economic and regulatory challenges associated with their development. Recently, stakeholders have endorsed a novel regulatory pathway to approve these lifesaving drugs for use in limited patient populations — namely those at highest risk and with few or no other options.
"As a nation, we need to exercise greater care with our use of antibiotics, in both humans and animals, so that these medications remain effective in treating serious bacterial infections."
SuperChefs Against Superbugs, an initiative of the Pew Campaign on Human Health and Industrial Farming, is a movement of chefs nationwide who have expressed their support of ending the misuse and overuse of antibiotics in food animal production. As a result, the SuperChefs are urging the Food and Drug Administration to strengthen its antibiotic policies.
It used to be easy to treat healthy children with common bacterial infections; a regimen of antibiotic pills could usually wipe out the disease. Today, patients might need to go home on intravenous antibiotics because oral therapies will no longer work. Antibiotic resistance is to blame.
A past bout of salmonella led Maine resident Danielle Wadsworth to travel to Washington, D.C. this week to argue for stronger regulations to curtail the use of antibiotics in livestock farming. She took part Wednesday in "Supermoms Against Superbugs," an initiative of the Pew Campaign on Human Health and Industrial Farming.
Dr. Cecilia Di Pentima is in Washington, D.C., for “Supermoms against Superbugs” to push for laws to curtail the use of antibiotics in livestock farming — one of many fronts in the battle to preserve the effectiveness of the medicines. Family physicians in the South, including Tennessee, have also been identified as inadvertent purveyors of drug-resistant bacteria by prescribing too many antibiotics.
Each year, tens of thousands of Americans die and hundreds of thousands are hospitalized because of bacterial infections resistant to antibiotics. Antibiotic overuse on industrial farms is a big part of the problem. The largest U.S. meat and poultry producers feed antibiotics to healthy animals over much of their lives to make them grow faster and to compensate for the overcrowded and unsanitary conditions in which they are bred and slaughtered.
On behalf of the undersigned organizations representing medical, public health, scientific, agricultural, environmental, animal protection, and other organizations, we urge you to include H.R. 820, the Delivering Antimicrobial Transparency in Animals (DATA) Act, as part of the final Animal Drug User Fee Act (ADUFA). This legislation provides a reasonable, common-sense approach to better understanding antibiotic use in agriculture.
"For decades, the meat industry has denied any problem with its reliance on routine, everyday antibiotic use for the nation's chickens, cows, and pigs. But it's a bit like a drunk denying an alcohol problem while leaning on a barstool for support. Antibiotic use on livestock farms has surged in recent years — from 20 million pounds annually in 2003 to nearly 30 million pounds in 2011."
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"Scientists at the Food and Drug Administration systematically monitor the meat and poultry sold in supermarkets around the country for the presence of disease-causing bacteria that are resistant to antibiotics. These food products are bellwethers that tell us how bad the crisis of antibiotic resistance is getting. And they’re telling us it’s getting worse."